Kleintje66 schreef op 11 februari 2021 10:33:
Francis Yahoo:
"the efficacy of aviptadil on the criterion of respiratory efficiency is very difficult to assess in the case of ARDS. For many reasons. 1 / Fragile patients in whom we can not stop the oxygen and even less the ventilator to assess the degree of improvement. it can quickly turn into a disaster that is difficult to recover. within the framework of an ARDS THE only interesting point to measure is what is called the shunt effect. Physiological reminder. all of your blood that passes through the lungs is oxygenated on contact with the alveoli. if 100% of the alveoli are functional, the situation is ideal: your blood will be oxygenated at best. if 25% of the alveoli are sick and 75% healthy we understand that 75% will be well oxygenated and 25% not at all. this 25% represents the shunt effect. presented on paper everything looks simple. to measure in patients, on the other hand, it is much more difficult because it requires several measurement points in the right ventricle; in the pulmonary artery etc. etc. On all the patients in a study this is strictly impossible. Hence the extreme importance of the radiological study which will be carried out because this shunt effect in the context of an ARDS is correlated with the degree of opacity of the radios."
Er zijn daar gelukkig ook mensen die er wel verstand van hebben in medische zin en die zijn ook positief over de resultaten.