beeldscherm schreef op 28 feb 2019 om 13:01:
Transgenic Mammals Likely To Transform Drug-Making.
Another area being pursued by researchers is the mass production of hemophiliac blood factors and other blood proteins. The American Red Cross set up an R&D transfusion biology lab about 10 years ago to help contain the growing problem of HIV contamination in the U.S. blood supply. "We were looking at what the future would be in terms of trying to replace some of the unsafe proteins," says Bill Drohan, senior director of plasma development at the American Red Cross's Holland Laboratory, the organization's research arm based in Rockville, Md. "We took two tacks: One [involved] ways of inactivating viruses in plasma and the other was trying to produce the proteins by recombinant technology."
Drohan notes that blood proteins had been made this way in tissue culture, but this was more expensive than isolating them from plasma. "So we looked at other ways of making it, and that's what brought us into the production of proteins in the milk of transgenic animals."